8

HPV16-E7 Antibody, Cy3 Conjugated

Details

HPV16-E7 Antibody, Cy3 Conjugated

Name

bs-10446R-Cy3

Catalog Number

350 EUR

Price

0.1ml

Size

More information

Antigen background

Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-HPV16-E7 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Specificity

This is a highly specific antibody against HPV16-E7. This antibody may also detect HPV35-E7

Source

KLH conjugated synthetic peptide derived from middle of HPV16-E7

Long name

HPV16-E7 Polyclonal Antibody, Cy3 Conjugated

Purification method

This antibody was purified via Protein A.

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

Excitation Emission

512,550nm/570,615nm

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Additional conjugation

cy3 conjugation kit

Synonyms

Protein E7; E7

Concentration

1ug per 1ul

Modification

Unmodified

Clonality

Polyclonal

French translation

anticorps

Tested applications

IF(IHC-P)

Immunogen_range

50-98/98

Target Antigen

HPV16-E7

Gene ID number

1489079

Swiss Prot

P03129

Crossreactive species details

HPV16

Crossreactivity

Virus

Modification site

None

Conjugation

Cy3

Back to top