Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation.
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
KLH conjugated synthetic peptide derived from HPV18 E6 protein
This is a highly specific antibody against HPV18 E6 protein.
HPV18 E6 protein (2F6) Monoclonal Antibody
HPV18 E6 protein (2F6) Monoclonal Antibody
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Purified by Protein G.
Unmodified antibody
Primary Antibodies
HPV18 E6 protein
IHC-P, IF(IHC-P)
Protein E6; E6
Unconjugated
1ug per 1ul
105-141/158
Monoclonal
anticorps
1489088
P06463
HPV18
Virus
None
2F6