Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.
For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
KLH conjugated synthetic peptide derived from middle of HPV16-E7
HPV16-E7 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
This is a highly specific antibody against HPV16-E7.
Anti-HPV16-E7 PAb ALEXA FLUOR 594
Rabbit (Oryctolagus cuniculus)
Conjugated Primary Antibodies
Alexa Fluor,ALEXA FLUOR® 594
Purified by Protein A.
Alexa conjugate 1
ALEXA FLUOR® 594
Protein E7; E7
1ug per 1ul