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HPV33 E7 Antibody, ALEXA FLUOR 488

Details

HPV33 E7 Antibody, ALEXA FLUOR 488

Name

bs-2969R-A488

Catalog Number

380 EUR

Price

100ul

Size

More information

Background of the antigen

E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-HPV33 E7 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Synonyms

E7 protein [Human papillomavirus type 33]; Human Papilloma Virus; Human papillomavirus type 33; Human papillomavirus type 33; Protein 33; early protein E7 [Human papillomavirus type 33].

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Long name

HPV33 E7 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Source

KLH conjugated synthetic peptide derived from HPV33 E7

Specificity

This is a highly specific antibody against HPV33 E7.

Also known as

Anti-HPV33 E7 PAb ALEXA FLUOR 488

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

Purification

Purified by Protein A.

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Conjugated with

ALEXA FLUOR® 488

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Excitation emission

499nm/519nm

Modification

Unmodified

Clonality

Polyclonal

French translation

anticorps

Tested applications

IF(IHC-P)

Immunogen range

30-80/97

Target Antigen

HPV33 E7

Subcellular location

Nucleus

Cross-reactive species details

HPV33

Crossreactivity

Virus

Modification Site

None

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