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Anti-HPV16 E6 + HPV18 E6 (Polyclonal), ALEXA Fluor 594

Details

Anti-HPV16 E6 + HPV18 E6 (Polyclonal), ALEXA Fluor 594

Name

GENTObs-1719R-A594

Catalog Number

489 EUR

Price

100 microliters

Size

More information

Background information

Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation.

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Antigen Source

synthetic peptide from HPV16 E6 + HPV18 E6 conjugated to KLH

Specificity

This antibody reacts specifically with HPV16 E6 + HPV18 E6

Modification

No modification has been applied to this antibody

Properties

For facs or microscopy Alexa 1 conjugate.

Also known as

HPV16 E6 + HPV18 E6 Polyclonal Antibody

Other name

Anti-HPV16 E6 + HPV18 E6 Polyclonal

Host organism

Rabbit (Oryctolagus cuniculus)

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Type

Conjugated Primary Antibody

Group

Polyclonals and antibodies

Purification method

Purified by Protein A.

Clone

Polyclonal Antibodies

Target Protein/Peptide

HPV16 E6 + HPV18 E6

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Clonality

Polyclonal Antibody

Conjugated with

ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1

Synonyms

Protein E6; E6

Cross Reactive Species details

HPV16/HPV18

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Applications

IF(IHC-P)

Gene ID

1489088

Swiss Prot

P06463

Cross reactive species

Virus

Modification site

None

Subcellular locations

N/A

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